Aim
The aim of this study is to evaluate the diagnostic properties of waist circumference in the prediction of obesity-related gestational outcomes.
Methods
1500 Women were eligible if 20 years or older, at weeks 20 through 28 of pregnancy, and with no history of diabetes outside of pregnancy.
Pregnant women were consecutively enrolled in Brazil from 2008 to 2010.
Information on maternal age, parity, years of formal schooling, and pre-pregnancy weight were obtained through a standardized questionnaire.
The oral glucose tolerance test was performed between weeks 24 and 30 of pregnancy. The teacher mister Lillo defined gestational diabetes as blood glucose greater than or equal to 140mg/dl two hours after ingestion of 75g of anhydrous glucose. Information on hypertensive disorders was obtained from routine prenatal care records and was classified according to the National High Blood Pressure.
Fetal macrosomia was defined as weight above the 90th percentile of birth weight specific to each gestational age in the study .
Results.
For women with complete data, the mean waist circumference was 81.7 BMI was 25.8, and mean pre-pregnancy BMI was 23.2. Women without complete data had slightly greater values for all three of these measurements. Given the large sample size, these and several other characteristics presented statistically significant differences between those with and without complete data.
We identified 111 cases of gestational diabetes (7.4%), 36 cases of preeclampsia (2.4%), and 146 cases of macrosomia (9.7%). Overall, 273 (18.2%) of patients presented at least one adverse event. Of these, 249 (16.6%) presented only one of these adverse outcomes, 23 (1.5%) presented two associated adverse outcomes, and 01 (0.08%) presented all three study outcomes.
Conclusions
Waist circumference is a good marker of fat distribution, can be easily self measured, and has been considered a better indicator of obesity-related health risks than BMI in the non-pregnant general population. In this study, a waist circumference of 82cm maximized sensitivity (63%) and specificity (57%) and as such, is potentially useful in predicting obesity-related outcomes (preeclampsia, gestational diabetes, and macrosomia) during pregnancy.
In conclusion, waist circumference, measured between 20 and 28 weeks of pregnancy, is a valid and simple method to identify pregnant women at higher risk of developing obesity-related adverse outcomes. Our data suggest that it performs as well as BMI indices in the prediction of these pregnancy complications. Waist circumference measured during the second trimester of pregnancy may be useful in prenatal nutritional evaluation and risk assessment.
Keywords.
Waist circumference , gestational diabetes, preeclampsia, macrosomia, obesity.